Monoclonal antibody targeting of mononuclear cell chemokines driving malignant pleural effusion
نویسندگان
چکیده
Recent evidence suggests that host immune cells contribute to the development of malignant pleural effusion (MPE), a common manifestation of metastatic cancer. We have identified such cells, predominantly mononuclear myeloid cells, recruited by tumor-orchestrated inflammatory chemokines. Moreover, targeting of these inflammation-associated mediators modified the disease course of MPE in mice.
منابع مشابه
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